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Theodorakis MJ, Carlson O, Michopoulos S, et al

How to Avoid Very Rapid Weight Loss When Using GLP-1 Drugs If your weight drops faster than expected, tell your clinician

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At one end of the spectrum, inadequate antioxidant defenses permit unchecked OS, leading to lipid peroxidation of sperm membranes, DNA fragmentation, and impaired sperm motility and viability

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The decreased absorption of cystine inhibits the synthesis of GSH, and the deficiency of GSH inactivates GPX4, which leads to a diminished reduction ability, resulting in the accumulation of lipid peroxides and ferroptosis